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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
11.08.2026journal-article

Hong Kong Journal of Occupational Therapy

Quantifying Electric-Powered Wheelchair (EPW) Driving Performance Using Jerk Metrics: A Pilot Study

Serena S. W. Ng, Chung Hang Tang, Stephen C. H. Tse, Alfred C. H. Yip, Winnie W. T. Lam

Background Current assessments of electric-powered wheelchair (EPW) driving, such as the Wheelchair Skills Test (WST), rely on observational scoring and lack validation in outdoor environments. Occupational Therapists require standardized, quantitative measures to evaluate driving performance and monitor training progress. Objective This pilot study examined: (1) the influence of cognitive, physical, and sensory components on EPW driving, (2) the validity of sensor-derived jerk metrics relative to WST scores, and ( …

10.08.2026journal-article

Neurorehabilitation and Neural Repair

Applying the International Classification of Functioning, Disability and Health to Classify Upper Limb Outcome Measures in Stroke Rehabilitation: A Construct-Driven Perspective

Canan Yuksel-Haji, Nicola Hancock, Allan Clark, Valerie M. Pomeroy

Introduction: Accurate evaluation of upper limb recovery after stroke is essential for guiding rehabilitation targeting specific impairments and activity limitations. To achieve this, outcome measures must clearly reflect what they assess, whether neuromuscular impairments or activity limitations. However, classification of measures is not always clear-cut, which can lead to misinterpretation of recovery progress and reduce rehabilitation planning effectiveness. Problem: Current classification practices often prior …

10.08.2026journal-article

Psychology and Psychotherapy: Theory, Research and Practice

‘So many relationships in the room’: Participant perspectives on the affordances and challenges of co‐therapy in psychedelic assisted therapy

Rachel Ham, John Gardner, Adrian Carter, Paul Liknaitzky

Abstract Objectives Psychedelic‐assisted therapy ( PAT ) frequently utilises a “cotherapy” model, in which two therapists jointly support participants throughout dosing and psychotherapy sessions. While common in clinical trials, participant experiences of cotherapy remain underexplored. This study explored cotherapy experiences in PAT with psilocybin for Generalised Anxiety Disorder ( GAD ). Design Longitudinal qualitative analysis of participants sampled from a large randomised, open‐label, phase 2 clinical trial …

10.08.2026journal-article

BMC Oral Health

Feasibility analysis of negative pressure wound therapy for odontogenic ascending necrotizing fasciitis: a single-center single-arm retrospective case series

Shu-Jun Chen, Ning Ji, Yu-Xuan Chen, Jian-Rui Xiao, Xiao-Zong Wei, Yan-Kun Liu, Lin-Wei Zhao

Abstract Background Odontogenic ascending necrotizing fasciitis (ANF) is an extremely rare, rapidly progressive, and destructive craniomaxillofacial necrotizing soft tissue infection. Advanced surgical drainage is essential to improve cure rates, shorten the disease course, and alleviate patient suffering. Methods This study was designed as a single-center, single-arm, retrospective feasibility case series. A total of 15 consecutive patients diagnosed with odontogenic ANF and treated with standardized NPWT from Mar …

10.08.2026journal-article

Bone & Joint Open

Occupational hazards in hip and knee adult reconstruction surgery

Matteo Innocenti, Roberto Civinini, Filippo Leggieri, Sébastien Lustig, Cécile Batailler, Simon N. van Laarhoven, Gijs van Hellemondt

Aims Adult reconstruction surgeons face unique occupational challenges during joint arthroplasty procedures, including sustained physical demands, ergonomic strain, noise exposure, and psychological pressure from high patient expectations. This systematic review aimed to synthesize existing evidence regarding physical and psychological stressors encountered by surgeons performing hip and knee arthroplasty. Methods Following PRISMA guidelines, we searched PubMed, EMBASE, Web of Science, and Cochrane Library through …

10.08.2026journal-article

Frontiers in Oncology

Impact of compounded financial collapse and armed conflict on access to radiation therapy in Lebanon: lessons for building resilient cancer care systems in fragile settings

Caroline Samaha Jabbour, Layth Mula-Hussain, Yavuz Anacak, Fadi El-Karak, Georges Fares, Toufic Eid, Hady Ghanem, Maria Pia Ibrahim, Christelle Saad, Maroun Khater

Background Lebanon’s radiation therapy (RT) system has been exposed to successive, overlapping crises since 2019, including financial collapse, the Beirut Port explosion, and armed conflict in 2024. This study analyzes the impact of compounded crises on RT access and practice patterns using longitudinal institutional data from Mount Lebanon Hospital (MLH) as a sentinel cohort. Methods A retrospective observational study was conducted at MLH (2018–2025). Annual treated patient volumes, treatment technique distributi …

10.08.2026journal-article

Revista de Terapia Ocupacional da Universidade de São Paulo

Literatura infantil na Terapia Ocupacional: um estudo orientado pela Classificação Internacional de Funcionalidade, Incapacidade e Saúde

Luísa Beltrame Lovatel, Fernanda de Sousa Marinho, Carolina Grego Del Cole

Developmental delay can impact different domains of occupational performance, requiring interventions that consider the child in their entirety. Occupational Therapy stands out for using playful resources as mediators of development, promoting participation and engagement in activities. Children's books, as a playful resource, enable the integration of cognitive, motor, and socioemotional aspects. The International Classification of Functioning, Disability and Health (ICF) can be used to structure assessment, clini …

10.08.2026journal-article

European Heart Journal - Digital Health

Machine Learning – Enhanced Baseline Risk Prediction Models for Cancer Therapy Related Cardiac Dysfunction: A Systematic Review and Critical Appraisal of Methodological Quality

Maria Sol Andres, Vijay Maharahan, Alexandra Pons Rivarola, Luis Garcia Rodriguez, Franck Thuny, Sivatharshini Ramalingam, Matilda Howe, Mamas A Mamas, Amitava Banerjee, Charlotte Manisty, Arjun K Ghosh, Aditya S Bharadwaj, Alexander R Lyon, Mohamed O Mohamed

Abstract Background Cancer therapy-related cardiac dysfunction (CTRCD) is a prevalent complication with adverse clinical implications. Guidelines have emphasised the need for reliable baseline risk prediction to guide prevention strategies. While machine learning (ML) has shown promise in cardiovascular medicine, the readiness of ML-based prognostic models for baseline CTRCD risk prediction in cardio-oncology remains unclear. Aim To systematically review and critically appraise the performance, methodological quali …

10.08.2026journal-article

Journal of Fiber Bioengineering and Informatics

Protective Vest for Reducing Occupational Exposure to Solar Heat Radiation

Uwe Reischl, Budimir Mijovic

Occupational exposure to solar heat radiation is a major contributor to heat stress among outdoor workers, particularly in agriculture, where physically demanding tasks are performed under high ambient temperatures and direct sunlight. Infrared (IR) radiation represents a significant external heat load that can impair thermoregulation even when convective and evaporative cooling are present. A key research gap addressed in this paper is the limited understanding of how garment materials simultaneously influence bot …

10.08.2026journal-article

Frontiers in Cell and Developmental Biology

Copper homeostasis and organelle-dependent mechanisms in bone metabolism: implications for osteoporosis therapy

Jialun Jiang, Jiawen Lin, Ziyu Zhou, Hongwei Pan, Pengju Zhao, Dandan Ma

Background Osteoporosis is a prevalent metabolic bone disorder driven by an imbalance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption, and current pharmacological options remain limited by adverse effects and incomplete mechanistic targeting. Copper, an essential trace element, has long been linked to bone mineral density through population-level dietary surveys, but whether and how copper mechanistically shapes osteoblast and osteoclast function at the subcellular level has not b …

10.08.2026journal-article

Frontiers in Oncology

Liquid biopsies for detection, characterization, and interception of therapy resistance in thoracic malignancies

Ezgi Oner, Volga M. Saini, Christina Cahill, Hannah O’Toole, Jennifer W. Li, Kathy Gately, Valsamo Anagnostou

Therapy resistance remains a leading cause of treatment failure and mortality in thoracic malignancies, despite major advances in targeted therapies and immunotherapies. Resistance evolves through heterogeneous, patient-specific mechanisms, including genetic alterations, epigenetic reprogramming, lineage plasticity, and tumor-microenvironment interactions, often emerging before radiographic progression or clinical relapse. Conventional tissue biopsies and imaging, while essential for diagnosis and treatment selecti …

10.08.2026journal-article

REMUNOM

Organización del Trabajo Ferroviario y Salud Ocupacional de los Maquinistas: Reflexiones sobre la Actividad Física, el Comportamiento Sedentario y la Calidad de Vida

Marcelo Henrique Correa Pimenta, Naruna Pereira Rocha, Valter Paulo Neves Miranda

La organización del trabajo ferroviario, caracterizada por jornadas laborales prolongadas, trabajo por turnos, elevadas demandas cognitivas y permanencia prolongada en posición sentada, puede afectar negativamente la salud ocupacional y la calidad de vida de los maquinistas ferroviarios. Este ensayo teórico-reflexivo tuvo como objetivo reflexionar críticamente sobre la influencia de la organización del trabajo ferroviario en la actividad física (AF), el comportamiento sedentario (CS), la salud ocupacional y la cali …

10.08.2026journal-article

Frontiers in Psychology

rTMS over bilateral superior temporal gyri combined with auditory-speech training for post-stroke pure word deafness: a case report

Xinxin Chen, Yichen Chang, Yan Leng, Xi Chen, Yongxue Li

Objective To describe the application of high-frequency rTMS over the bilateral superior temporal gyri (STG) combined with auditory-speech training and assess its effects on auditory comprehension. Methods A 54-year-old woman with PWD secondary to bilateral temporal ischemic strokes underwent a 10-day combined intervention. She received 10 Hz rTMS over the left STG, followed by auditory-speech training, and then received rTMS over the right STG with identical parameters. Treatment outcomes were assessed using the W …

10.08.2026journal-article

Journal of Occupational & Environmental Medicine

Gender and season disparities in the influence of short-term fine particulate matter exposure on emergency room visits for mood disorders in Taiwan

Su-Lun Hwang, Yu-Ching Lin, Chieh-Mo Lin, Miao-Ching Chi

Objective: This study examined the short-term effects of fine particulate matter (PM 2.5 ) exposure on emergency room (ER) visits for mood disorders, specifically bipolar disorder (BD) and depressive disorder (DD), in Taiwan. Methods: A time-stratified case-crossover design combined with distributed lag non-linear models was used to analyze data from the Taiwan Ministry of Environment and the Chang Gung Research Database (2010-2020). Results: Among 2,172 identified ER visits, PM 2.5 exposure was significantly assoc …

10.08.2026journal-article

South African Baptist Journal of Theology

The Role and Impact of Absent Father Figures in the Rehabilitation of Incarcerated Youth

Eben Jacques Philip Mourries, Shantelle Weber

Absent fathers in South Africa are physically, emotionally, and relationally unavailable to their children, disengaging from paternal responsibilities, moral guidance, and affective support. Empirical and theological scholarship associates absent fathers with adverse developmental outcomes, including emotional insecurity, behavioural challenges, impaired moral reasoning, and increased vulnerability to delinquency. This article explores the role and impact of absent father figures in the rehabilitation of incarcerat …

10.08.2026journal-article

International Journal For Multidisciplinary Research

Effectiveness of Chewing Technique on Vocal Phonation among Speech Language Pathology Students: A Pilot Study

Ameena P T, Satish Kumaraswamy

Voice is an essential tool for communication and professional performance, particularly among speech-language pathology students who are exposed to high vocal demands. The present study aimed to evaluate the effectiveness of the chewing technique on vocal phonation among female speech-language pathology students. Thirty female students aged 18–20 years were randomly assigned to an experimental group (n = 16) and a control group (n = 14). The experimental group practiced the chewing technique for 8 weeks, while the …

10.08.2026journal-article

Cancers

Cancer Stem Cells in Colorectal Cancer: From Molecular Mechanisms to Diagnosis, Prognosis and Therapy Implications

Dami Aiyejuto, Ananya Luthria, Thompson Hui, Anitha Kota Shenoy

Colorectal cancer (CRC) remains a major cause of cancer-related mortality, with recurrence and treatment resistance as persistent challenges. Increasing evidence supports the cancer stem cell (CSC) model in CRC, in which a subpopulation of self-renewing colorectal cancer stem cells (CCSCs) sustains tumor growth, metastasis, and therapy resistance. CCSCs are increasingly recognized as key drivers of tumor progression, therapeutic resistance, and relapse, and are increasingly being investigated not only as therapeuti …

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10.08.2026journal-article

Frontiers in Oncology

Oral selective estrogen receptor degraders and biomarker-driven therapy in ER-positive breast cancer: mechanisms, clinical evidence, and future directions

Anton Yu Alasheev, Raneem Hamama, Elena V. Petersen, Philipp Y. Maximov

Breast cancer (BC) remains one of the most prevalent malignancies worldwide, with approximately 70% of cases being estrogen receptor-positive (ER+). Endocrine therapy targeting the estrogen receptor has revolutionized BC treatment, evolving from surgical oophorectomy to selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs). Selective estrogen receptor degraders (SERDs) represent the latest advancement in hormonal therapy, offering complete receptor blockade and degradation. This review compr …

10.08.2026journal-article

Future Internet

Bimodal Speech Emotion Recognition Using a Hybrid CNN-LSTM Architecture with Sentiment Fusion

Tze-Syn Yap, Lee-Yeng Ong

Speech emotion recognition (SER) is a fundamental task in affective computing; however, traditional unimodal approaches often struggle to capture the complex emotional cues present in spontaneous conversational speech. Bimodal frameworks that integrate acoustic and textual information have therefore emerged to provide complementary semantic and acoustic representations. This study proposes a bimodal SER framework based on a hybrid convolutional neural network–long short-term memory (CNN–LSTM) architecture. Using th …

10.08.2026journal-article

Developmental Medicine & Child Neurology

Speech, language, social communication, and communication assessments in Rett syndrome: A systematic review

Lucas N. Raniolo, Ruth O. Braden, Jana von Hehn, John Christodoulou, David N. Lieberman, David J. Amor, Adam P. Vogel

Abstract Aim To provide a systematic overview of speech, language, and social abilities of people with Rett syndrome (RTT), and identify the most frequently used communication assessments in the literature. Method A systematic search of PubMed, CINAHL, ScienceDirect, ERIC, and speechBITE databases was conducted using terms synonymous with RTT, speech, language, social, and clinical assessment. Two independent reviewers screened abstracts; one reviewer conducted full‐text screening, communication‐related data extrac …

10.08.2026journal-article

P.A. Herzen Journal of Oncology

Ribociclib-based combination endocrine therapy in elderly and frail patients: key issues of efficacy, safety, and drug interactions requiring the attention of an oncologist

I.V. Kolyadina

This review presents the findings of the most consequential large-scale randomized controlled trials and real-world practice studies on combination endocrine therapy with ribociclib in elderly patients with advanced HR-positive, HER2-negative breast cancer. Phase 3 and 3b randomized clinical trials (MONALEESA-2, MONALEESA-3, and CompLEEment-1) have consistently demonstrated that endocrine therapy combined with ribociclib confers a significant advantage over endocrine monotherapy in reducing the risks of disease rec …

10.08.2026journal-article

Hospital Pharmacy

When the Law Changes Therapy: Interrupted Time-Series Analysis of the Regulatory Impact on Intravenous Analgesic Consumption in 2 Italian Orthopaedic Hospitals (2021-2024)

Barbara Crivelli, Luca Galassi, Beatrice Faitelli, Giorgio Oriani, Benedetta Angela Maurizio, Davide Picco, Carlo Banfi, Federica Pieri

Objectives: Tramadol is a centrally acting weak opioid widely used for moderate postoperative pain in orthopaedic surgery, so its regulatory status is directly relevant to hospital pharmacists. In November 2022 the Italian Ministry of Health reclassified tramadol as a controlled substance under Section A of Presidential Decree 309/1990. Its effect on surgical-hospital prescribing has not been systematically described. We quantified the change in consumption and expenditure of intravenous (IV) tramadol and of the IV …

10.08.2026journal-article

Asian Journal of Research in Biochemistry

Microbial Interventions in Cancer Therapy: Molecular Mechanisms, Engineering Strategies and Translational Constraints

Ummulkhairi Tukur, Imran Yahaya Umar, Aminat Oyiza Musa, Hassan Ibrahim Zogirma, Abdullahi Umar Muhammad, Ibrahim Sammani Auwal, Precious A. Idakwoji

Microbial interventions are being developed as anticancer agents, local drug factories, replicating immunotherapies and modifiers of treatment response. Their appeal arises from properties that conventional medicines do not readily reproduce: active replication, environmental sensing, penetration of poorly perfused tissue, programmable payload production and the capacity to engage innate and adaptive immunity. This critical narrative review evaluates tumour-targeting bacteria, engineered bacterial therapeutics, onc …

10.08.2026journal-article

Problems of Balneology, Physiotherapy and Exercise Therapy

Сравнительный анализ тарифной политики санаторно-курортных организаций в системе обязательного и добровольного медицинского страхования как фактор финансовой доступности реабилитации

М. В. Деребизова, Н. Н. Мусинова, А. В. Мухачева, Н. С. Сергиенко, Х. Б. Монахова

Introduction: Sanatorium-resort rehabilitation is an integral component of the restorative treatment system in the Russian Federation. According to Rosstat data, in 2024 the sanatorium-resort services market volume reached 220.08 billion rubles with 7.3 million consumers; however, existing financing mechanisms through the compulsory (CHI) and voluntary (VHI) health insurance systems are characterized by significant tariff differentiation that reduces the financial accessibility of rehabilitation services for variou …