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Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
24.08.2026journal-article

Frontiers in Dementia

Nature-based interventions for people living with dementia and their carers: a scoping review

Manpreet K. Gill, Shareefa Thekkan, Danine Irwin

Introduction Nature-based interventions are increasingly recognised as a promising non-pharmacological approach to support people living with dementia and their carers. Although a growing body of research has explored the relationship between nature engagement and dementia, the evidence remains dispersed across a wide range of intervention types, settings and outcome measures. This review aimed to identify and map the available evidence relating to nature-based interventions for people living with dementia and thei …

24.08.2026journal-article

Revista ft

Envelhecimento facial associado ao uso da tirzepatida: alterações estéticas e estratégias de manejo na harmonização orofacial – revisão integrativa da literatura.

Adriana Karollayne Silva Pedroso, Andréia Gomes Moreira

Introduction: Tirzepatide represents an important therapeutic advance in the treatment of obesity and type 2 diabetes mellitus, promoting significant weight loss. However, this weight reduction can cause changes in facial aesthetics, popularly known as Ozempic face, characterized by volume loss, skin laxity, and accentuation of facial wrinkles, making the role of Orofacial Harmonization (OF) relevant in managing these changes. Objective: To analyze, through an integrative literature review, the main facial aestheti …

24.08.2026journal-article

Transactions of the Institute of British Geographers

The Housing Crisis as a Failure of Distribution: The Mismatch of Homes to Places and Space to People in England and Wales, 1991 to 2021

Gauthier Dulout, Nissa Finney, David McCollum

ABSTRACT The housing crisis in England and Wales is commonly explained as a national shortage of housing supply, leading to a policy focus on aggregate production targets. This paper challenges that narrative, arguing that this framing has obscured a parallel dimension: a growing spatial mismatch between where homes are and where they are needed, compounded by deepening inequalities in how the existing stock is occupied. Using Local Authority District (LA) data from four decennial censuses (1991 to 2021), this stud …

24.08.2026journal-article

Frontiers in Aging Neuroscience

Striatal small RNA remodeling in MPTP-induced Parkinson’s disease highlights coordinated downregulation of mitochondrial tsRNAs

Mingyu Mao, Yan Wang, Qing Deng, Jun Xiang, Wentao Li

Parkinson’s disease (PD) is characterized by progressive nigrostriatal degeneration, yet the contribution of modification-rich small RNAs to PD pathology remains unclear. Here, we used PANDORA-seq to profile the striatal small RNA landscape in a subacute MPTP-induced mouse model of PD. MPTP-treated mice exhibited significant motor deficits together with reduced striatal tyrosine hydroxylase and dopamine transporter expression, confirming successful model establishment. Small RNA profiling revealed that transfer RNA …

24.08.2026journal-article

Multilingua

I Was in Ventimiglia! Traces, signs and voices from people on the move: a participatory ethnography of graffiti at a border choke point

Lucia Aletto

Abstract Since 2015, Ventimiglia has become a “choke point” for “people on the move” traversing turbulent routes conditioned by restrictive European border policies. This article employs a participatory ethnography of graffiti to offer a singular perspective on undocumented movements. By treating graffiti as “participatory objects” rather than mere artifacts, the study documents approximately 250 units geolocated between the Roya river’s informal camp and Grimaldi shelters. The methodology emphasizes “spontaneous p …

24.08.2026journal-article

Brain

Diabetes and neurodegeneration in cognitively unimpaired older adults: implications for cognition

Amaryllis A Tsiknia, Victoria R Tennant, Marylan Davison, Rajesh Nandy, Matthew Borzage, Alexandra L Clark, Arthur W Toga, Kristine Yaffe, Sid O’Bryant, Meredith N Braskie

Abstract Type 2 diabetes mellitus is associated with cognitive impairment and greater Alzheimer’s disease risk, with cross-sectional studies suggesting that this is driven by neurodegeneration and vascular changes. Longitudinal studies, however, report similar rates of total brain atrophy over time in diabetic and non-diabetic adults. We recently showed that diabetes-related neurodegeneration in cognitively unimpaired adults is regional and may not be evident in longitudinal studies of global brain atrophy. The mec …

24.08.2026journal-article

Dementia

Understanding Dance Facilitation in Dementia Care: A Qualitative Study Using Socio-Ecological-Relational Framework

Anthony Scerri, Charles Scerri

Dance-based interventions are increasingly recognised as valuable psychosocial approaches to support the wellbeing and social participation of people living with dementia. However, existing research has largely focused on outcomes, with limited attention to how such programmes are facilitated and experienced in practice. This study explored how dance facilitators understand and navigate the multi-level influences shaping the organisation, delivery and perceived impact of dance sessions for people living with dement …

24.08.2026journal-article

Addiction

Clinicians' and people who use drugs' perspectives on artificial intelligence in addiction medicine

Patrick J. A. Kelly, Elizabeth Chen, Amelia Bailey, Katie Biello, Brandon D. L. Marshall, Josiah D. Rich, Jaclyn M. W. Hughto

Abstract Background and aims Artificial intelligence (AI) may improve addiction medicine workflows and health outcomes but raises questions about data privacy and unintended harms for people who use drugs (PWUD). This qualitative study aimed to understand the perspectives of clinicians and PWUD regarding perceived benefits and concerns about clinical AI in addiction medicine. Design A qualitative study with one‐on‐one semi‐structured interviews about AI. Setting Addiction medicine clinicians in Rhode Island ( n = 7 …

24.08.2026journal-article

Revista sanitaria de investigación

PREVENCIÓN DE CAÍDAS EN MEDICINA INTERNA: CASO CLÍNICO DE UNA PACIENTE MAYOR CON FRACTURA PERTROCANTÉREA Y HEMATOMA SUBDURAL AGUDO.

Lucía Cantón Ramos, Avelina Cachón Villadangos, Javier Francisco Merillas Alija

Las caídas intrahospitalarias constituyen un evento adverso especialmente relevante en las personas mayores, debido a su origen multifactorial y a las posibles consecuencias sobre la morbimortalidad, la autonomía funcional y la duración de la hospitalización. Se presenta el caso de una mujer de 82 años, ingresada en una unidad de Medicina Interna por descompensación de una enfermedad renal crónica, con antecedentes de enfermedad de Alzheimer y diabetes mellitus. La paciente presentaba riesgo alto de caídas, con una …

24.08.2026journal-article

International Journal of Molecular Sciences

Aptamer-Based Platforms for Human Aging Biomarkers: Multiplexed Proteomics, Biosensors and Translational Perspectives

Zulfiya Guvatova, Anastasiya Kobelyatskaya, Alexander Gorbunov, Elena Pudova, Alexey Moskalev

Aptamer-based multiplexed proteomic platforms, especially the SOMAmer-based SomaScan assay, are widely used for large-scale discovery of circulating biomarkers relevant to human aging. This review summarizes 42 original research articles published from 2020 through 2026 in which aptamers or aptamer-derived biosensors were used to characterize aging-related biomarkers in human samples or clinically relevant human-disease contexts. The eligible literature falls into several thematic areas: whole-plasma and organ-spec …

24.08.2026journal-article

ACM Transactions on Computer-Human Interaction

NetGauge Games Platform: Connecting People and Place while Crowdsourcing Broadband Measurements

Jared Duval, Cole Pendergraft, Taylen Johnson, Olivia Vester, Chaithanya Heblikar, Hunter Beach, Shelby Hagemann, Md Nazmul Hossain, Varna Gobbur, Alison Graham, Morgan Vigil-Hayes

Collecting measurements of mobile broadband (cellular Internet) performance is critical for efforts addressing digital disparities. However, collecting measurements at the necessary spatiotemporal scales to identify performance and coverage gaps is non-trivial. Crowdsourced data collection is a scalable approach to gathering mobile broadband performance data. However, existing platforms for crowdsourced mobile broadband measurements are not designed to engage workers over time or space, which can lead to spatial mi …

24.08.2026journal-article

Journal of Neuroscience Research

Distinct Cognitive and Structural Correlates of Pain Extent and Central Sensitization Symptoms in Older Women and Men With Chronic Pain

Keiko Yamada, Hiroki Tabata, Kaito Takabayashi, Hitoshi Naito, Hideyoshi Kaga, Koji Kamagata, Yoshifumi Tamura

ABSTRACT Chronic pain in later life may be accompanied by alterations in brain structure and cognition, but whether pain extent and central sensitization symptoms identify distinct brain‐behavior patterns remains unclear. We examined associations of pain extent and central sensitization symptoms, assessed using the 9‐item Central Sensitization Inventory (CSI‐9), with regional gray matter volume and cognitive function in community‐dwelling older adults. This cross‐sectional study included 272 participants with chron …

24.08.2026journal-article

eceee Summer Study proceedings

Keep people in the loop: co-designing personal preference agents for energy flexibility

Michael Fell

Extended abstract 1-066-26 Large Language Model (LLM) agents are increasingly used to simulate human perspectives in domains such as research and design. There is evidence that at the population level, LLM agents can perform reasonably well in replicating general trends apparent in research with humans, including on the topic of energy. This approach is of interest because of the very significant time- and cost-efficiencies agents offer. However, substantial concerns also exist. Such models have demonstrated potent …

24.08.2026journal-article

INTERNATIONAL JOURNAL OF SOCIAL SCIENCES AND MANAGEMENT RESEARCH

Security Dynamics and Socio-Economic Development in South-East, Nigeria: A Case of Indigenous People of Biafra (IPOB) Sit-At-Home Order

Nduka kenneth Omede,

An environment devoid of security threat is not only needed for human existence but also a critical factor that determines the Social economic development of every country, region or state. The study hopes to examine the effect of Indigenous People of Biafra (IPOB) sit-at-home order on the socio-economic development in South east Nigeria. Three hypotheses were formulated to ascertain if there are significant relationships existing between the two intervening variables. Survey research design was adopted and structu …

24.08.2026journal-article

Journal of the American Geriatrics Society

Mechanisms of Benefit in Geriatric Assessment ( GA ): Approach‐Oriented Coping Mediates Outcomes of a GA ‐Guided Supportive Care Intervention ( GAIN ‐S)

Cristiane Decat Bergerot, Paulo Gustavo Bergerot, Marianne Razavi, Marcos Vinicius da Silva França, Jose Adolfo Cerveira, William Hiromi Fuzita, Errol J. Philip, Carlos Gil Moreira Ferreira, Marco Murilo Buso, Ryan Nipp, Areej El‐Jawahri, Enrique Soto‐Perez‐de‐Celis, William Dale

ABSTRACT Background Older adults with metastatic cancer often experience declines in physical function, emotional well‐being, and quality of life (QOL). Geriatric assessment and management (GAM) have shown promise in addressing these challenges, but underlying mechanisms remain unclear. This study explored coping strategies as potential mediators for improvements in physical function, depression, and QOL. Methods For this secondary analysis of a randomized controlled trial, older adults (≥ 65 years) with metastatic …

24.08.2026journal-article

International Economic Review

Local Shocks and Regional Dynamics in an Aging Economy

Yuta Suzuki

ABSTRACT This paper studies how population aging shapes regional adjustment to local shocks. I develop a dynamic spatial general equilibrium model that incorporates aggregate demographic change, life‐cycle variation in migration and employment choices, and forward‐looking investment in local capital. Applying the model to Japan, I find that aging can mitigate welfare losses from a negative local shock. Although older populations are less mobile, reduced outmigration sustains local capital demand and slows capital d …

24.08.2026journal-article

Journal of Clinical Medicine

Behavioral and Clinical Correlates of Poor Sleep and Anxiety Symptoms in Adults Aged 50 Years and Older: A Cross-Sectional Study

Hammad S. Alhasan, Mansour Abdullah Alshehri

Background/Objectives: Sleep quality, anxiety symptoms, physical activity, musculoskeletal pain, and multimorbidity are interrelated health domains, but evidence examining these factors together among adults aged ≥50 years in Saudi Arabia remains limited. This study described their prevalence and assessed cross-sectional associations among these domains. Methods: A cross-sectional online survey using convenience sampling was conducted in Saudi Arabia between December 2024 and April 2025. Participants completed meas …

24.08.2026journal-article

Revista Chilena de Rehabilitación y Actividad Física

Impacto del entrenamiento de fuerza resistencia en la satisfacción vital y capacidad funcional de personas mayores en Temuco

Beatriz Almendras Suazo

Objective: To determine the impact of a strength-endurance exercise program on functional capacity and life satisfaction in older adults in the city of Temuco. Methodology: Quasi-experimental study with a single-group pre-post design. The sample (n=12) was non-probabilistic convenience sampling, composed of individuals over 60 years of age from a community club. Participants underwent a 10-week strength-endurance training program, with one 60-minute group session per week, supervised by a physical therapist. Functi …

24.08.2026journal-article

International Journal of STD & AIDS

Acute kidney injury among hospitalized people living with HIV

Alice Doubinsky, Aude Theunissen, Rita Ghaleb, Marc Delforge, Maria Garjau, Nicolas Dauby

Objectives To describe the clinical characteristics, aetiologies, severity, and short-term outcomes of acute kidney injury (AKI) among hospitalized people living with HIV in a European tertiary HIV referral center. Methods This cross sectional analysis included adults living with HIV who developed AKI during hospitalization at Saint-Pierre University Hospital, Brussels, between 2007 and 2016. AKI was defined according to Kidney Disease: Improving Global Outcomes (KDIGO) serum creatinine criteria. Aetiologies, clini …

24.08.2026journal-article

Evidencia actualizacion en la práctica ambulatoria

Magnesio para el manejo del insomnio en adultos mayores

Ingrid Annabel Benjaminsen

La suplementación con magnesio es promocionada publicitariamente para el tratamiento del insomnio, aunque la evidencia que respalda su eficacia permanece incierta. A partir de la consulta de una paciente de 72 años, la autora revisó la evidencia sobre la efectividad y seguridad de este mineral en los trastornos del sueño. Los hallazgos sugieren un beneficio modesto, reflejado en una reducción de 17 minutos en el tiempo para conciliar el sueño en comparación con el placebo y mejoras subjetivas en la calidad del desc …

24.08.2026journal-article

The FASEB Journal

A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging

Jianfei Gong, Xiaolin Xu, Jian Han, Jinze Yang, Mengyuan Tian, Jie Yan, Jie Qiao

ABSTRACT Genomic instability is a key driver of ovarian aging, impairing granulosa cell (GC) function and diminishing ovarian reserve. However, the regulatory mechanisms underlying GC genomic homeostasis remain poorly defined. This study investigates the novel role of DELTEX2 (DTX2) in maintaining GC genomic stability and its underlying mechanism in the DNA damage response during ovarian aging. Our data show that telomere length was significantly shortened in both ovarian tissues and isolated GCs from aged mice. Me …

24.08.2026journal-article

Transdigital

Análisis descriptivo de la marcha mediante sensores inerciales y evaluación clínica en personas mayores

Verónica Hernández Valle, Mayra Patricia González Hernández, José Héctor Manuel Frías-Vázquez Mellado, María Eustolia Pedroza Vargas

El proceso del envejecimiento lleva a un descenso gradual de las capacidades físicas y mentales, y un mayor riesgo de enfermedad. Las personas mayores son especialmente sensibles a disminuir su capacidad locomotora. El objetivo de la investigación fue evaluar la marcha de las personas mayores mediante sensores inerciales y evaluación clínica. El estudio fue de tipo descriptivo mediante una evaluación clínica que incluyó el análisis de: longitud de miembros inferiores, desnivel escapular, desnivel pélvico, capacidad …

24.08.2026journal-article

PLOS One

Perspectives of frail older adults and family caregivers on Urinary Incontinence interventions: A qualitative study

Maureen O.’ Callaghan, Dylan Williams, Emma Geraghty, Rachel Hosey, Amanda Clifford, Katie Robinson

Background Urinary incontinence (UI) is highly prevalent among older adults living with frailty and is associated with substantial social, emotional, financial, environmental, and caregiver-related burdens. UI is underreported, underassessed and undertreated in this population. Little is known about older adults’ perspectives and experiences of interventions for UI. Aim This study aimed to explore the experiences and views of older adults with frailty and family caregivers on conservative, pharmacological and surgi …

24.08.2026journal-article

Frontiers in Nutrition

A DGA-aligned pulse-protein diet may support iron homeostasis in older adults: an exploratory analysis of the PRODMED1 trial

Bruna O. de Vargas, Jessica L. Freeling, Saba Vaezi, Moul Dey

Background/objectives Iron homeostasis is essential for healthy aging, yet whether Dietary Guidelines for Americans (DGA)–aligned diets support iron status in older adults remains unclear, particularly when iron is provided exclusively as non-heme iron. This exploratory secondary analysis of PRODMED1 examined iron-related outcomes, and nutrient-responsive signals involving methionine and FGF21 in older adults consuming DGA-aligned meat- and pulse-protein diets. Methods In an 18-week randomized crossover controlled- …