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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
17.08.2026journal-article

The Journal of ECT

Klazomania Refractory to Electroconvulsive Therapy

Vishwa Thakkar, Sagar Karia, Nilesh Shah

Klazomania is a rare phenomenon characterized by compulsive, uncontrollable shouting or yelling without an emotional trigger or reason. It has been reported to be associated with various psychiatric and neurological conditions. No specific treatment has been recommended as the etiology is not known. Trials of antipsychotics, antidepressants, and antiepileptic drugs have been used. Hereby, we report a case of Klazomania in a patient with Obsessive Compulsive Disorder who initially responded to Electroconvulsive Ther …

17.08.2026journal-article

Adolescência e Saúde

Freedom Of Speech And Expression In The Digital Age: A Critical Analysis Of Constitutional Rights, Social Media Regulation, And Emerging Technologies

Dr. Mamta Rani, Dr. Jitendra Yadav

Freedom of speech and expression constitutes one of the fundamental pillars of a democratic society. In India, Article 19(1)(a) of the Constitution guarantees every citizen the right to freedom of speech and expression, while Article 19(2) permits reasonable restrictions in the interests of sovereignty, security, public order, decency, morality, contempt of court, defamation, and incitement to an offence. The emergence of digital technologies, social media platforms, artificial intelligence (AI), algorithmic govern …

17.08.2026journal-article

Clinical Rehabilitation

A systematic review of early neuroimaging and neurophysiological biomarkers for post-stroke mobility prognostication

Cristina Levy, Emily J Dalton, Jennifer K Ferris, Bruce CV Campbell, Amy Brodtmann, Sandra Brauer, Leonid Churilov, Kathryn S Hayward

Objective Prognostication may help guide mobility rehabilitation planning and goal setting post-stroke. This systematic review aimed to examine the prognostic capacity of early neuroimaging and neurophysiological biomarkers of mobility outcomes up to 24 months post-stroke. Data sources MEDLINE/EMBASE was searched from inception to May 2026. Cohort studies that reported neuroimaging or neurophysiological biomarkers measured <14 days post-stroke and mobility outcome(s) assessed >14 days but ≤24 months post-stroke wer …

16.08.2026journal-article

Journal of Intensive Care

Prognostic associations of urine output in AKI and dialysis vintage in ESKD at continuous kidney replacement therapy initiation in ICU patients

Keisuke Okamoto, Naoki Ozu, Hidetada Fukushima, Masahiko Kawaguchi, Kazuhiko Tsuruya

Abstract Background Prognostic assessment at continuous kidney replacement therapy (CKRT) initiation remains challenging in ICU practice. CKRT recipients are heterogeneous; most have acute kidney injury (AKI), whereas a clinically important subset has end-stage kidney disease (ESKD). We evaluated whether pre-CKRT urine output in AKI and dialysis vintage in ESKD were associated with short-term prognosis after CKRT initiation. Methods We conducted a single-center retrospective cohort study of consecutive adults who s …

16.08.2026journal-article

Internal Medicine Journal

Adjunctive metformin therapy in type 1 diabetes in pregnancy: insights from an Australian cohort

Mauli Govinna, Joanna Gong, Jessica Triay, Dev Kevat

Abstract Metformin has gained attention as a potential adjunct therapy in pregnant women with type 1 diabetes mellitus (T1DM), although evidence is limited. We present the first reported experience of metformin use in pregnant women living with T1DM who used continuous glucose monitoring to monitor glycaemic outcomes. In our multicentre case series, metformin use was associated with an increased time in range and reduced glycaemic variability, supporting potential use in pregnant women with T1DM.

16.08.2026journal-article

Journal of Medical Rehabilitation

Medical rehabilitation and health resort treatment in patients with cardiovascular diseases

V. V. Shipulin

Background. Cardiovascular diseases (CVD) remain among the leading causes of mortality and disability, thereby underscoring the clinical and socioeconomic relevance of medical rehabilitation and secondary prevention. Cardiac rehabilitation uses a multidisciplinary approach that includes exercise training, modifying risk factors, educating patients, providing psychosocial support, and improving adherence. Objective: To summarize recent data on effective methods of medical rehabilitation and health resort treatment f …

16.08.2026journal-article

Bali Medical and Wellness Journal

Nutritional Therapy Based on ESPEN Guidelines in a Patient with Ascending Colon Non-Hodgkin Lymphoma Undergoing Chemotherapy with Decreased Oral Intake and Infectious Complications: A Case Report

Ni Komang Saraswita Laksmi

Background: Malnutrition is a frequent complication in patients with cancer undergoing chemotherapy due to increased metabolic requirements, treatment-related adverse effects, and infectious complications. Gastrointestinal disturbances such as nausea, dysphagia, and opportunistic infections may worsen food intake and increase the risk of malnutrition. Case Description: A 66-year-old woman with ascending colon non-Hodgkin lymphoma undergoing the fourth cycle of R-CHOP chemotherapy was hospitalized with pneumonia, or …

16.08.2026journal-article

Acta Medica Alanya

The Prognostic Significance of the NOLUS Score in Patients with Metastatic Breast Cancer Receiving CDK 4/6 Inhibitor Therapy

Ece Ulukal Karancı, Halil Göksel Güzel, Mustafa Özgür Arıcı, Mehmet Acun

Aim: Breast cancer is the most common cancer, and in the metastatic hormone-positive group, CDK-4-6 inhibitors are used. We aimed to examine the prognostic value of the “NOLUS” score, calculated from the estrogen receptor (ER), progesterone receptor (PR), and Ki-67 index, in patients with breast cancer receiving CDK 4/6 inhibitors.Materials and Methods: This retrospective single-center study included 76 patients with HR+/HER2- metastatic breast cancer who were treated with CDK 4/6 inhibitors (ribociclib or palbocic …

16.08.2026journal-article

Journal of Sustainable Research in Applied Sciences

Knowledge, Attitudes, and Barriers to Vital Pulp Therapy among Dental Practitioners in Zliten, Libya: A Cross-Sectional Study

Abdalmagid Rajab Alhammaly, Mustafa Ahmed Ben Hkoma

خلفية الدراسة: شهد مجال طب الأسنان التحفظي تحولاً جذرياً نحو الفلسفة الأساسية المتمثلة في التدبير العلاجي طفيف التوغل لطب اللب. وبدلاً من اللجوء التلقائي إلى علاجات الجذور التقليدية العنيفة وغير العكسية، تولي الأطر السريرية الحديثة الأولوية لعلاج اللب الحيوي (VPT) لإنقاذ الأنسجة اللبية المتضررة من النخر العميق أو الصدمات الميكانيكية. تقيم هذه الدراسة المسحية المقطعية مستوى المعرفة، والمواقف، والعوائق التشغيلية المتعلقة ببتر اللب الجزئي والكلي بين ممارسي طب الأسنان في مدينة زليتن، ليبيا. الأهداف: يتمثل الهدف الرئيسي …

16.08.2026journal-article

Healthcare

Procedural Optimization of Capsaicin 8% Patch Therapy Using Ultrasound-Guided Bilateral Ankle Nerve Block in Painful Diabetic Peripheral Neuropathy: A Retrospective Comparative Cohort Study

Hassan Moria

Background: Application of the capsaicin 8% patch is commonly associated with treatment-related burning pain, which may necessitate rescue analgesia, compromise completion of the standardized 60 min application, and reduce acceptance of repeat treatment. Although capsaicin is an established therapy for painful diabetic peripheral neuropathy (PDPN), evidence supporting strategies to improve procedural tolerability remains limited. This study evaluated whether ultrasound-guided bilateral ankle nerve block (UGBANB) wa …

16.08.2026journal-article

Journal of Esthetic and Restorative Dentistry

Long‐Term Esthetic‐Functional Rehabilitation of Unilateral Cleft Lip and Palate With a Cross‐Arch Monolithic Zirconia Fixed Dental Prosthesis Following Multidisciplinary Treatment: 5‐Year Post‐Prosthetic Follow‐Up

Gizem Altundal, Sinem Gümüş, Erol Kozanoğlu, Sevde Şirikçi Biberci, Asuman Deniz Gümrü Çelikel

ABSTRACT Objective This case report describes the esthetic‐functional rehabilitation of a patient with unilateral complete cleft lip and palate who was managed multidisciplinarily from 10 to 18 years of age, and reports the clinical outcome 5 years after definitive prosthetic rehabilitation, which was undertaken after late secondary alveolar bone grafting had yielded insufficient bone volume for implant placement. Clinical Considerations Phased orthodontic treatment from age 10–17 (slow maxillary expansion, fixed a …

16.08.2026journal-article

Revista Científica Kosmos

Efectos de la bailoterapia en el fortalecimiento del trabajo en equipo en funcionarios del GADMC Bolívar

Andrea Alexandra Pozo Mena, Daniela Thalia Manrique Muñoz

Objetivo: Analizar los cambios en el trabajo en equipo asociados a la implementación de un programa de bailoterapia en los funcionarios del Gobierno Autónomo Descentralizado Municipal del cantón Bolívar, considerando las dimensiones de comunicación, cooperación, confianza interpersonal e integración grupal como elementos relevantes para fortalecer las relaciones laborales. Metodología: Se desarrolló una investigación con enfoque cuantitativo, alcance descriptivo-comparativo y diseño cuasiexperimental de tipo pretes …

16.08.2026journal-article

Journal of Medical Rehabilitation

Advanced rehabilitation approaches for patients with malignant neoplasms of the respiratory system

O. V. Kovaleva

Malignant neoplasms (MNs) of the respiratory system remain among the leading causes of oncological morbidity and mortality worldwide. Despite substantial advances in surgical treatment, systemic therapy, and radiotherapy, many patients experience reduced functional reserve, impaired physical performance, respiratory symptoms, and diminished quality of life. Therefore, rehabilitation has become an essential component of comprehensive cancer care throughout the treatment continuum. This review summarizes findings on …

16.08.2026journal-article

Journal of Clinical Medicine

Efficacy and Safety of Moderate-Dose Stereotactic Body Radiation Therapy (SBRT) for Patients with Oligometastatic Lung Cancer Unfit for Standard SBRT: A Preliminary Single-Center Study

Jaehyeon Park, Bong Kyung Bae, Min Kyu Kang, Jongmoo Park

Background/Objectives: Stereotactic body radiation therapy (SBRT) is increasingly used for oligometastatic lung cancer. However, standard ablative SBRT (BED10 of 100 Gy or higher) is not feasible when lesions abut critical organs or patients have poor performance status. This study aimed to evaluate the efficacy and safety of moderate-dose SBRT (BED10 below 100 Gy but exceeding conventional palliative doses) in patients with oligometastatic lung cancer unfit for standard ablative SBRT. Methods: We retrospectively a …

16.08.2026journal-article

Journal of Medical and Health Studies

Barriers to the Implementation of Phase I Cardiac Rehabilitation from the Perspective of Medical Staff Based on Normalisation Process Theory: A Qualitative Study

Rongrong Yang, Yingchun Liu, Jiayi Mao, Lihua Shi

Background/Objectives: Based on the Normalisation Process Theory (NPT), this study aims to systematically analyze the barriers to knowledge translation of Phase I cardiac rehabilitation (CR) from the perspective of medical staff. Methods: Purposive sampling and snowball sampling were used to recruit 12 members of the cardiac rehabilitation multidisciplinary team for one-on-one in-depth interviews. Colaizzi’s seven-step phenomenological analysis method was employed to organize and summarize the interview data. Resul …

16.08.2026journal-article

Revista ft

Tratamento endodôntico em incisivo superior em abscesso periapical crônico com uso de laserterapia e cimento à base de silicato de cálcio: relato de caso clínico

Keissy Helem Portela de Aguiar, Maria Ivete Formiga Relvas Neta, Amanda Caroline Neves Reis, Laura Sofia Alves Araújo Reis, João Bosco Formiga Relvas

Endodontic treatment has as its main objective the disinfection of the root canal system and the preservation of the dental element in function. However, factors such as caries can favor the development of pulpal and periapical alterations, such as pulp necrosis and chronic periapical abscess. In this context, adjuvant therapies, such as photodynamic therapy (PDT) and the use of bioceramic biomaterials associated with calcium silicate-based cements, have been employed with the aim of enhancing disinfection and stim …

16.08.2026journal-article

Special journal of the Medical Academy and other Life Sciences

COMPARATIVE ANALYSIS OF BIOIDENTICAL AND CONVENTIONAL HORMONE REPLACEMENT THERAPY IN MENOPAUSAL WOMEN: CLINICAL EFFICACY, SAFETY PROFILE, ECONOMIC IMPACT, AND CROSS-COUNTRY PERSPECTIVES Authors

Chavan Akanksha Mahendra

Background: Menopause is a significant physiological transition characterized by declining ovarian hormone production and associated vasomotor, urogenital, psychological, and metabolic symptoms. Hormone Replacement Therapy (HRT) remains a cornerstone of menopausal symptom management; however, concerns regarding its long-term safety have increased interest in Bioidentical Hormone Replacement Therapy (BHRT). Differences in healthcare accessibility, socioeconomic conditions, and cultural attitudes further influence tr …

16.08.2026journal-article

Advanced Healthcare Materials

Targeted NIR‐II Photothermal Therapy Enabled by Bioorthogonal Click Reaction With Olympicenyl Radical Nanoparticles

Mingzhe Wang, Xingchi Liu, Jinlian Hu, Yijia Luo, Lang Huang, Lei Ye, Lan Ma, Zhe Sun

ABSTRACT This study presents an application of delocalized hydrocarbon neutral monoradical, an olympicenyl radical ( OR6 ), as a high‐performance organic photothermal agent (PTA) for targeted photothermal therapy (PTT). By encapsulating OR6 into functionalized nanoparticles (d OR6 ‐NPs), a remarkable near‐infrared‐II (NIR‐II) absorption at 1056 nm and photothermal conversion efficiency (PCE) of 84.66% are achieved. To overcome the limitations of passive tumor targeting, a bioorthogonal “tag‐and‐target” strategy is …

16.08.2026journal-article

Journal of Medical Rehabilitation

Changes in quality of life among patients with cervical cancer undergoing rehabilitation: a prospective cohort study

S. A. Akavova, A. E. Ivanov, S. V. Bulgakova

Background. Cervical cancer (CC) remains a significant problem in gynecologic oncology, occupying leading positions in the morbidity structure among women. Current treatment methods have a substantial impact on the quality of life (QoL) of patients. However, data on the dynamics of QoL during the rehabilitation process in patients with CC across different stages are insufficient. Objective: To analyze the QoL dynamics during the rehabilitation period in CC patients who received various treatment modalities over a 3 …

16.08.2026journal-article

Macromolecular Symposia

The Mammalian Target of Rapamycin(mTOR) Signaling Pathway and mTOR Inhibitors in Cancer Therapy

Sony Devassy, Mridula Sreedharan, Saju Joseph, Sulekha K M, Abhay Raju, Sabu Thomas

ABSTRACT The mammalian target of rapamycin (mTOR) serine/threonine protein kinase known to be an important regulator of cellular growth, protein translation, cell proliferation, cell survival, metabolism, and autophagy. It is known to be activated by intracellular as well as extracellular signals, such as nutrient availability, growth factors, and energy levels of cells. The frequent deregulation of mTOR signaling in over 30% of malignancies makes it a promising key target for cancer therapy. Many mTOR inhibitors h …

16.08.2026journal-article

Journal of Medical Rehabilitation

Evolution of quality of life concepts and changes in their assessment in medical rehabilitation

Т. V. Konchugova, V. V. Ivanova, L. N. Sandzhieva

The assessment of a patient’s quality of life (QoL) is an integral part of personalized treatment and rehabilitation programs. Although this method of assessing health status has been widely used, the past 10 years have seen prerequisites emerge for transforming this group of tools. This study reviews the evolution of concepts regarding patient QoL and changes in approaches to its assessment. Various methods are presented, ranging from questionnaires focused on social well-being to forms and scales used in routine …

16.08.2026journal-article

Journal of Medical Rehabilitation

Analysis of rehabilitation needs in patients with dementia in Russia

М. V. Ipatova, Yu. А. Pokrovsky, Т. А. Solokhina

Background. Dementia is one of the leading causes of disability among older adults that requires significant rehabilitation services. In Russia, the population aging is expected to increase the number of people with dementia and associated functional limitations. However, rehabilitation needs for this condition have not been quantitatively assessed. Objective: To estimate the magnitude and trends in rehabilitation need of people with Alzheimer's disease and other dementias in Russia. Material and methods. A seconda …

16.08.2026journal-article

Journal Of Babylon Center for Humanities Studies

أفعال الكلام وتجلياتها في ديوان (هكذا أُنَقِّبُ) للشاعر كرم الأعرجي _دراسة تداولية_

عمر خضر محيميد

الملخَّص: يهدف هذا البحث إلى الكشف عن أفعال الكلام التي مثَّلت مقاصد الشاعر وغاياته في ديوان (هكذا أنقِّب), فهي رسائل بثَّها الشاعر إلى المتلقي؛ ليجعله مشاركا له في تجاربه ومشاعره بلغة إبداعية تميل إلى الرمزية تارة وإلى كسر أفق التوقع تارة أخرى، ولما كانت نظرية أفعال الكلام تعنى بدراسة اللغة في استعمالاتها المختلفة مبدية عناية كبيرة بسياقي المقال والمقام والعرف الاجتماعي ومقاصد المتكلمين, فقد اخترت أن تكون وسيلتي للكشف عن مقاصد الشاعر وأفعال الكلام التي أنجزها في ديوانه. وقد اشتمل البحث على مبحثين يسبقهما تمهيد وتل …

16.08.2026journal-article

Journal of Medical Rehabilitation

Multimodal approach to managing patients with myofascial pain syndrome

D. F. Khritinin

Myofascial pain syndrome (MPS) is a common disorder involving localized or referred pain that originates from trigger points in muscles and fascia. In many cases, its treatment is either inappropriate or delayed, leading to a reduced quality of life for patients. This is due to incomplete comprehension of the mechanisms underlying myofascial pain, the lack of uniform diagnostic criteria, and the absence of standard treatment protocols. This review aims to summarize, systematize, and evaluate the available data on t …